Chris Backhouse

Journal Papers (Last 6 years)

These are the recent publications of my research group, the Applied Miniaturisation Lab., or AML. We recently moved from Alberta (2011), with temporary quarters (2011-2013) until our lab was completed in the Quantum Nano Centre (QNC) in late 2013. The Older Publication tab and the Gallery tab provide further details.

2013-14 (in Waterloo)

• Integration of Organic Light Emitting Diodes and Organic Photodetectors for Lab-on-a-Chip Bio-Detection Systems
  G. Williams, C. Backhouse, H. Aziz
  Electronics 2014, 3(1), 43-75; doi:10.3390/electronics3010043  
  

• An optical relay approach to very low cost hybrid polymer-complementary metal-oxide semiconductor electrophoresis instrumentation
  G. H. Hall, D. Sloan, T. Ma, M. Couse, S. Martel, D. Elliott, M. Glerum, C. Backhouse
  J.Chromatography A (2014) Volume: 1349 122-128 DOI: 10.1016/j.chroma.2014.05.005  
  

• Fabrication and characterization of aluminum thin film heaters and temperature sensors on a photopolymer for lab-on-chip systems
  J. Martinez-Quijada, S. Caverhill-Godkewitsch, M. Reynolds, L.  Gutierrez-Rivera, R. W. Johnstone, D. G. Elliott, D.  Sameoto, C. J.  Backhouse
  Sensors and Actuators A (2013) 193 170-181

• PDE Modeling of a Microfluidic Thermal Process for Genetic Analysis Application
  R. Khosroushahi, H. Marquez,J. Martinez-Quijada, C. Backhouse
  J. Applied Mathematics (2013) Article 767853 DOI: 10.1155/2013/767853  
  

2012    (in Waterloo)

• Variation of thermal and mechanical properties of KMPR due to processing parameters
  M. Reynolds, A. Elias , D. Elliott, C. Backhouse, Dan Sameoto
  J. Micromech. Microeng. 22 (2012) 125023 (12pp)  
  

• Multilayer bonding using a conformal adsorbate film (CAF) for the fabrication of 3D monolithic microfluidic devices in photopolymer
  L. Gutierrez-Rivera, J. Martinez-Quijada, R. Johnstone, D. Elliott, C. Backhouse and D. Sameoto
  J. Micromech. Microeng. (2012) 22 085018 (12pp)  
  

• Microfluidic approach to genotyping human platelet antigens
  C. Lim, D. P. Manage, A. Atrazhev, G. Denomme, C. J. Backhouse, J. P. Acker
  IET Nanobiotechnology (2012) 6(2) 33-39  
  

• Inhibition of on-chip PCR using PDMS-glass hybrid microfluidic chips
  H. Crabtree, J. Lauzon, Y. Morrissey, B. Taylor, T. Liang, R. Johnstone, A. J. Stickel, D. Manage, A. Atrazhev, C. J. Backhouse, L. Pilarski
  Microfluidics and Nanofluidics (2012) 13, 383-398  
  

• Nonlinear Controller Designs for Thermal Management in PCR Amplification
  J. Jiang, G. Kaigala, H. Marquez and C.J. Backhouse
  IEEE Transactions On Control Systems Technology (2012) 20 11-30  
  

• Millimeter scale separation of DNA with a replaceable polymer matrix
  D. Manage, ; D. Elliott, C. Backhouse
  Electrophoresis (2012) 33 3213-3221  
  

2011    (Alberta and Waterloo)

• Assessing the performance and longevity of Nb, Pt, Ta, Ti, Zr, and ZrO 2 -sputtered Havar foils for the high-power production of reactive [ 18 F ]F by proton irradiation of [ 18 O]H 2 O
  J. S. Gagnon, J. S. Wilson, E. Sant, C. J. Backhouse, S. A. McQuarrie
  Applied Radiation and Isotopes (2011) 69 (10) 1330-1336  
  

2010    (at U. of Alberta)

• Towards robust cellular image classification: theoretical foundations for wide-angle scattering pattern analysis
  P. M. Pilarski, C. J. Backhouse
  Biomedical Optics Express (2010) 1(4) 1225-1233 
  

• Development of a microfluidic chip-based plasmid miniprep
  D. Moira Glerum, V. Northrup, C. Backhouse
  Analytical Biochemistry (2010) 402 185-190  
  

• Integrated circuit-based instrumentation for microchip capillary electrophoresis
  M. Behnam, G. Kaigala, M. Khorasani, S. Martel, D. Elliott, C. Backhouse
  IET Nanobiotechnology (2010) 4 91-101  
  

• Fluorescent Carrier Ampholytes Assay for Portable, Label-Free Detection of Chemical Toxins in Tap Water
  M. Bercovici, G. Kaigala, C. Backhouse, J. Santiago
  Anal. Chem. (2010) 82 1858-1866  
  

• A scalable and modular lab-on-a-chip genetic analysis instrument (Cover)
  G. V. Kaigala,  M. Behnam, A. C. E. Bidulock,  R. W. Johnstone, D. G. Elliott, C. J.  Backhouse
  Analyst (2010) 135 1606-1617
  

• Miniaturized system for isotachophoresis assays
  G. V. Kaigala,  M. Bercovici, M. Behnam,  D. G. Elliott, J. G. Santiago, C. J.  Backhouse
  Lab on a chip (2010) 10 2242-2250

• System design and modelling of a time-varying, nonlinear temperature controller for microfluidics
  G.V. Kaigala, J. Jiang, C. Backhouse, H. Marquez
  IEEE Trans. on Control Systems Technology (2010) 18 521-530 (DOI: 10.1109/TCST.2009.2015937)  
  

2009    (at U. of Alberta)

• High-Voltage CMOS Controller for Microfluidics
  Khorasani, Maziyar; Behnam, Mohammad; van den Berg, Leendert; et al.
  IEEE Transactions on Biomedical Circuits and Systems (2009) 3 89-96  
  

• Light scattering characterization of mitochondrial aggregation in single cells
  X. Su, K. Singh, W. Rozmus, C. Backhouse, C. Capjack
  Optics Express (2009) 17 13381-13388  
  

• Inexpensive, USB-powered and fully portable lab on a chip-based capillary electrophoresis instrument
  G. V. Kaigala, M. Behnam, C. Bliss, M. Khorasani, S. Ho, J.N. McMullin, D. G. Elliott and C. Backhouse
  IET Nanobiotechnology (2009) Vol. 3, Issue 1, pp. 1-7  
  

2008    (at U. of Alberta)

• Readily integrated, electrically controlled microvalves
  W. H. Song, J. Kwan, G. V. Kaigala, V. N. Hoang, C. J.  Backhouse
  J. Micromechanics and Microengineering (2008)  18 Article #045009  
  

• An inexpensive and portable microchip-based platform for integrated RT-PCR and capillary electrophoresis (Cover)
  G. V. Kaigala, V. N. Hoang, A. Stickel, J. Lauzon, D. Manage, L. M.  Pilarski, C. J.  Backhouse
  Analyst (2008) 133  331-338
  

• An integrated microfluidic chip for chromosome enumeration using fluorescence in situ hybridization (FISH)
  Sieben, Vincent J.; Debes-Marun, Carina S.; Pilarski, Linda M.; Backhouse, Christopher J.
  Lab on a chip (2008) 8 2151-2156  
  

• Integrated wavelength-selective optical waveguides for microfluidic-based laser-induced fluorescence detection
  Bliss, Christopher L.; McMullin, James N.; Backhouse, Christopher J.
  Lab on a chip (2008) 8 143-151  
  

• Strategies for enhancing the speed and integration of microchip genetic amplification
  V. N. Hoang, G. Kaigala, A. Atrazhev, L. Pilarski, C. Backhouse
  Electrophoresis (2008) 29 4684-4689  
  

• Elemental analysis using micro-laser-induced breakdown spectroscopy (LIBS) in a microfluidic platform
  Y. Godwal, G. Kaigala, V. Hoang, S. Lui, C. Backhouse, Y. Tsui, R. Fedosejevs
  Opt. Express (2008) 16 12435-12445 
  

• Rapid simulation of wide-angle scattering from mitochondria in single cells
  P. M. Pilarski, X. Su, D. M. Glerum, C. Backhouse
  Opt. Express (2008) 16 12819-12834  
  

• An integrated CMOS high voltage supply for lab-on-a-chip systems
  M. Behnam, G. V. Kaigala, M. Khorasani, P. Marshall, C. Backhouse, D. G. Elliott
  Lab Chip (2008) 8 1524-1529  
  

• A microfluidic study of mechanisms in the electrophoresis of scDNA
  D. Manage, I. Imriskova-Sosova, D. M. Glerum, C. Backhouse
  Electrophoresis (2008) 29 2466-2476  
  

• Electrically controlled microvalves to integrate microchip PCR and capillary electrophoresis,
  G. Kaigala, V. Hoang, C. Backhouse
  Lab Chip (2008) 8 1071-1078  
  

• Measurements of light scattering in integrated microfluidic waveguide cytometers
  X. Su, K. Singh, C. Capjack, J. Petrek, C. Backhouse, W. Rozmus
  J. Biomedical Optics (2008) 13 2 024024  
  

• Dynamic temperature measurement in microfluidic devices using thermochromic liquid crystals
  V. N. Hoang, G. Kaigala, C. Backhouse
  Lab Chip (2008) 8 484-487